Reshaping the Future of New Materials with Synthetic Biology
Lingzhu Spider Biotechnology focuses on the R&D and large-scale production of high-performance recombinant spider silk proteins and bio-based dyes. Leveraging carbon-negative innovative production processes, it injects revolutionary green technological momentum into industries such as cosmetics and skincare, textile fabrics, and advanced new materials.
Corporate Development Milestones
A Complete Innovation Journey from Laboratory Research Breakthroughs to Million-Ton Industrial Production
2020 - 2021
Company Establishment · Construction of Proprietary Spider Silk Protein Gene Library
The team completed whole-genome sequencing and in-depth sequence analysis of multiple native spider species from Southern China, built a proprietary database containing millions of exclusive spider silk protein sequences, and successfully developed the industry-unique integrated “spider silk protein + bio-pigment” ecological dyeing and weaving process.
- Whole-Genome Sequencing and Analysis of Native Spider Species
- Construction of a Million-Level Recombinant Spider Silk Protein Gene Sequence Database
- Breakthrough of Eco-Bio Dyeing Technology Beyond Traditional Textile Processes
2022 - 2023
Efficacy Validation · Pilot-Scale Fermentation Process Implementation
Completed efficacy testing and application validation of spider silk functional proteins in skincare, cosmetics, and personal care fields; in 2023, fully achieved pilot-scale amplification of spider silk regenerated fiber protein, and completed high-strength recombinant spider silk wet-spinning under laboratory standards.
- Cross-Industry Empowerment: Efficacy Validation of Skin Repair Raw Materials
- Process Breakthrough: Successful Pilot Fermentation of High-Density Engineered Bacterial Cell Factories
- Industry First: Recombinant Spider Silk Protein Fiber Wet-Spinning Molding Technology
2024 - 2025
Million-Ton Industrial Fermentation · Deep Collaboration with Domestic and International Brands
In 2024, completed the development of high-density production processes using ton-scale fermenters, unlocking the large-scale fermentation pathway for textile-specific functional spider silk proteins; in 2025, achieved commercial mass production of recombinant spider silk protein powder raw materials with an annual capacity reaching the ton level, initiated joint testing and in-depth project collaborations with leading domestic and international brands, and was recognized as a National High-Tech Enterprise.
🛡️ Independent Intellectual Property Barriers
Accumulated applications in the fields of synthetic biology and new materials18 invention patents, of which7 invention patents have been granted, with strategic deployment of2 PCT international patents。
Carbon-Negative Closed-Loop Production Process
Emulating natural biological functions to achieve efficient, low-carbon, and environmentally friendly large-scale fiber production
Gene Design and Sequence Optimization
Leveraging an AI-powered intelligent gene editing platform to conduct logical design, iterative optimization, and precise recombinant modification of the molecular structure of natural spider silk proteins.
Microbial Cell Factory Fermentation
Introducing optimized gene sequences into high-efficiency engineered strains (E. coli/yeast) and achieving high-density large-scale fermentation amplification through industrial bioreactors.
Protein Purification and Wet Spinning
Using environmentally friendly green solvents to fully dissolve recombinant spider silk proteins, preparing bio-protein powder through patented purification processes, and then feeding it into spinning equipment for wet-forming.
Multi-Functional Finished Textile Fabrics
Breaking through the performance boundaries of traditional fabrics to create low-carbon, green new yarns and high-performance fabrics, featuring ultra-high tensile strength, lightweight properties, and natural bioactivity.
Core Scientists and Management Team
Deep Integration of Top-Tier Scientific Research Capabilities and Mature Industrial Commercialization Expertise
Liang Qing
Founder / Chief Executive OfficerSerial entrepreneur with 20 years of industry experience, proficient in the commercialization of cutting-edge technologies and the construction of full-industry-chain closed loops.
- Long-term technology transfer collaborations with the MIT Media Lab and Lawrence Berkeley National Laboratory.
- Former consultant at a top global advisory firm, providing strategic planning services to dozens of large manufacturing enterprises including Foxconn.
- Possesses mature capabilities in international business negotiation and integration of upstream and downstream channels.
Wang Boxiang
Founder / Chief Technology OfficerOver a decade of experience in synthetic biology innovation and industrial-scale production of recombinant proteins.
- Graduate of Wuhan University, former core R&D scientist at BGI and Bluepha.
- Core researcher in Academician Yang Huanming's synthetic biology research group.
- Led the team to win the iGEM Global Grand Championship three times, served as a competition judge, and solved the core challenges in the fermentation scale-up of recombinant spider silk proteins.
Meng Qing
Chief ScientistRenowned expert in biomaterials and biomimetic materials, doctoral supervisor at Donghua University.
- Pioneered the use of gene-edited silkworms to produce full-length spider silk proteins, with results published in October 2023 in *Matter*, a flagship journal of Cell Press, sparking global industry coverage.
- Over 20 years of in-depth research on spider silk gene encoding and fiber expression, leading more than 20 national-level scientific research projects.
- Published over 100 high-level academic papers in top international journals such as *Nature Chemical Biology*.
Partnering with Lingzhu to usher in a new era of biomaterials.
Open to global brand strategic collaborations in skincare and cosmetics, fashion textiles, and advanced new materials sectors. Welcome to request sample test reports and technical white papers.
